Almost forty years after its inception by Richard Feynman, as the first quantum technology ever proposed, quantum simulation is now witnessing accelerating progress at the hardware as well at the software level. A variety of platforms, from atomic, molecular and optical (AMO) physics to solid-state systems are being investigated. Quantum advantage (the ability to outperform simulations on classical supercomputers) is being achieved in first demonstrations. Concrete applications in fields as diverse as condensed matter theory, high-energy physics and physical chemistry are being addressed. Major funding programs at European and national level support both academic research and industrial development. The programme will offer a forum for players from the whole spectrum of areas mentioned above to exchange ideas and identity promising future directions to shape the future of the field.